Which effect is typical of both pramlintide and liraglutide?

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Pramlintide and liraglutide both enhance satiety, which contributes to their effectiveness in managing blood glucose levels and aiding in weight control. Pramlintide is an amylin analog that works by slowing gastric emptying and increasing the feeling of fullness, which diminishes post-meal glucose spikes. Liraglutide, a GLP-1 receptor agonist, also promotes satiety by acting on the central nervous system to reduce appetite. This dual action of both medications helps patients feel more satisfied with smaller amounts of food, thereby assisting them in better glucose regulation and weight management.

While both drugs do share some other effects, such as delaying gastric emptying, the enhancement of satiety is a primary therapeutic goal that directly addresses the behavioral aspects of eating, which is vital for individuals managing diabetes.

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