What time will the action of intermediate-acting insulin typically end if given at 0800?

Intermediate-acting insulin, such as NPH insulin, typically has a duration of action of about 10 to 16 hours. When administered at 0800, the peak action generally occurs around 4 to 6 hours later. Therefore, the onset of action begins shortly after administration, with significant activity during the afternoon and into the evening.

Given this timeline, if you consider the duration of the insulin's action, it would typically continue to influence blood glucose levels until approximately 1800 to 0200. This means that the correct answer reflects the expected end time of the insulin's action within that duration, covering both evening and overnight periods when blood glucose regulation remains crucial.

In this context, the other options do not align with the pharmacokinetics of intermediate-acting insulin. For instance, the first option suggests a terminal action time that falls too early to accommodate the full duration of action, while the latter options extend beyond the expected operational timeline of such insulin type.