What is the duration of lispro's effects?

Lispro is a fast-acting insulin analog, and its primary role is to effectively manage postprandial blood glucose levels. After administration, lispro generally has a rapid onset of action, peaking quickly within a couple of hours. The duration of its effects typically spans approximately 3 to 5 hours, which is considered ideal for managing blood glucose levels around mealtime.

This duration allows individuals using lispro to experience a significant reduction in blood glucose following meal intake, thereby minimizing the risk of postprandial hyperglycemia. Understanding the pharmacokinetics of lispro is crucial for determining the optimal timing for administration, especially in relation to food intake. This is why recognizing that the duration of lispro’s effects is accurately captured as 3 to 5 hours is key for effective glucose regulation management.