What effect does NPH insulin primarily have on blood glucose levels?

NPH insulin, or Neutral Protamine Hagedorn insulin, is a type of intermediate-acting insulin often utilized in diabetes management. Its primary function is to help lower blood glucose levels. After administration, NPH insulin works by facilitating the uptake of glucose by tissues, particularly muscle and fat, and by inhibiting the liver’s production of glucose. This results in a reduction of blood sugar levels following meals.

It is also important to understand that NPH insulin is designed to provide a more prolonged action compared to rapid-acting insulins, which means its effects can last several hours. This characteristic allows for better control of blood glucose levels throughout the day, particularly when taken in conjunction with meals. As a result, its main impact is to lower hyperglycemia.

While other effects may be associated with blood glucose management, such as stabilization of glucose levels over time or the variability in glucose levels that can arise from not using insulin properly, the key action of NPH insulin itself is to effectively reduce blood glucose levels in individuals with diabetes.