Insulin isophane suspension is classified as what type of insulin?

Insulin isophane suspension, often referred to as NPH (Neutral Protamine Hagedorn) insulin, is classified as an intermediate-acting insulin. This classification is based on its pharmacokinetics, which includes a slower onset of action compared to rapid-acting and short-acting insulins, and a moderate duration of action.

Intermediate-acting insulins like isophane typically begin to take effect within 1 to 3 hours after administration, peak in action around 4 to 12 hours, and continue to work for approximately 12 to 18 hours. This characteristic makes them particularly useful for providing basal insulin coverage throughout the day and night, helping to manage blood glucose levels effectively between meals and overnight.

The other categories of insulin have distinct profiles: rapid-acting insulins act within minutes and are ideal for controlling postprandial (post-meal) glucose spikes; short-acting insulins have a slightly longer duration than rapid-acting but still primarily focus on meal coverage; while long-acting insulins provide a consistent release of insulin over an extended period, typically lasting 24 hours or more. Understanding these differences helps healthcare providers choose the appropriate type of insulin based on a patient’s individual